Serotonin antagonists

Pharmacologic specificity of antidepressive activity by monoaminergic neural transplants

Psychopharmacology / Depression / Immunohistochemistry / Serotonin / Female / Animals / Frontal Cortex / Learned Helplessness / Norepinephrine / Rats / Forced Swim Test / Neural Transplantation / Sciatic Nerve / Pineal Gland / Frontal Lobe / Serotonin antagonists / Motor activity / Adrenal Medulla / Animals / Frontal Cortex / Learned Helplessness / Norepinephrine / Rats / Forced Swim Test / Neural Transplantation / Sciatic Nerve / Pineal Gland / Frontal Lobe / Serotonin antagonists / Motor activity / Adrenal Medulla

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Physicochemical and biopharmaceutical characterization ofendo-2-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-2,3-dihydro-1H-benz[e]isoindol-1-one (CR3124) a novel potent 5-HT3 receptor antagonist

Water / Scanning Electron Microscopy / Powder Diffraction / NMR Spectroscopy / Crystallization / Macromolecular X-Ray Crystallography / Molecular Dynamics / Crystal structure / Humans / Liver / Differential scanning calorimetry / Permeability / Pharmaceutical Sciences / Animals / Male / Solubility / Citrus / Intestinal absorption / Caco-2 cells / Rats / X ray diffraction / Carbon Tetrachloride / Molecular Conformation / Flavones / Drug Stability / Crystalline Structure / Drug Induced Liver Injury / Serotonin antagonists / Aspartate Aminotransferases / Alanine Transaminase / Macromolecular X-Ray Crystallography / Molecular Dynamics / Crystal structure / Humans / Liver / Differential scanning calorimetry / Permeability / Pharmaceutical Sciences / Animals / Male / Solubility / Citrus / Intestinal absorption / Caco-2 cells / Rats / X ray diffraction / Carbon Tetrachloride / Molecular Conformation / Flavones / Drug Stability / Crystalline Structure / Drug Induced Liver Injury / Serotonin antagonists / Aspartate Aminotransferases / Alanine Transaminase

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Physicochemical and biopharmaceutical characterization ofendo-2-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-2,3-dihydro-1H-benz[e]isoindol-1-one (CR3124) a novel potent 5-HT3 receptor antagonist

Water / Scanning Electron Microscopy / Powder Diffraction / NMR Spectroscopy / Crystallization / Macromolecular X-Ray Crystallography / Molecular Dynamics / Crystal structure / Humans / Liver / Differential scanning calorimetry / Permeability / Pharmaceutical Sciences / Animals / Male / Solubility / Citrus / Intestinal absorption / Caco-2 cells / Rats / X ray diffraction / Carbon Tetrachloride / Molecular Conformation / Flavones / Drug Stability / Crystalline Structure / Drug Induced Liver Injury / Serotonin antagonists / Aspartate Aminotransferases / Alanine Transaminase / Macromolecular X-Ray Crystallography / Molecular Dynamics / Crystal structure / Humans / Liver / Differential scanning calorimetry / Permeability / Pharmaceutical Sciences / Animals / Male / Solubility / Citrus / Intestinal absorption / Caco-2 cells / Rats / X ray diffraction / Carbon Tetrachloride / Molecular Conformation / Flavones / Drug Stability / Crystalline Structure / Drug Induced Liver Injury / Serotonin antagonists / Aspartate Aminotransferases / Alanine Transaminase

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Inactivation of 5-HT2C Receptors Potentiates Consequences of Serotonin Reuptake Blockade

Neuropsychopharmacology / Serotonin / Animals / Male / Synaptic Transmission / Microdialysis / Rats / Wistar Rats / Brain Chemistry / Serotonin antagonists / Serotonin Uptake Inhibitors / Selective serotonin reuptake inhibitor / Microdialysis / Rats / Wistar Rats / Brain Chemistry / Serotonin antagonists / Serotonin Uptake Inhibitors / Selective serotonin reuptake inhibitor

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Evaluation of radioiodo-4-amino-N-[1-[3-(4-fluorophenoxy)-propyl]-4-methyl-4-piperidinyl]-5-IODO-2-methoxybenzamide as a potential 5HT2 receptor tracer for SPE(C)T

Membranes / Brain / Animals / Male / Clinical Sciences / Radioactive Tracers / Serotonin Receptors / Rats / Single Photon Emission Computed Tomography / Radioligand Assay / Wistar Rats / Serotonin antagonists / Isotope Labeling / Radioactive Tracers / Serotonin Receptors / Rats / Single Photon Emission Computed Tomography / Radioligand Assay / Wistar Rats / Serotonin antagonists / Isotope Labeling

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The Putative Atypical Antipsychotic Drug Amperozide Preferentially Increases c-fos Expression in Rat Medial Prefrontal Cortex and Lateral Septum

Neuropsychopharmacology / Immunohistochemistry / Prefrontal Cortex / Nucleus Accumbens / Serotonin / Dopamine / Animals / Male / Statistical Significance / Amygdala / Rats / Basal ganglia / Atypical Antipsychotics / Wistar Rats / Serotonin antagonists / Medial Prefrontal Cortex / Dopamine / Animals / Male / Statistical Significance / Amygdala / Rats / Basal ganglia / Atypical Antipsychotics / Wistar Rats / Serotonin antagonists / Medial Prefrontal Cortex

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Inactivation of 5-HT2C Receptors Potentiates Consequences of Serotonin Reuptake Blockade

Neuropsychopharmacology / Serotonin / Animals / Male / Synaptic Transmission / Microdialysis / Rats / Wistar Rats / Brain Chemistry / Serotonin antagonists / Serotonin Uptake Inhibitors / Selective serotonin reuptake inhibitor / Microdialysis / Rats / Wistar Rats / Brain Chemistry / Serotonin antagonists / Serotonin Uptake Inhibitors / Selective serotonin reuptake inhibitor

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Serotonin receptor sensitivity in major depression

Depression / Bipolar Disorder / Biological Sciences / Biological Psychiatry / Humans / Prolactin / Female / Male / Depressive Disorder / Serotonin Receptors / Adult / Serotonin antagonists / Prolactin / Female / Male / Depressive Disorder / Serotonin Receptors / Adult / Serotonin antagonists

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Azabicyclic indole esters as potent 5-HT4 receptor antagonists

Organic Chemistry / Animals / Serotonin Receptors / Bioorganic and medicinal Chemistry / Colon / Structure activity Relationship / Serotonin antagonists / Structure activity Relationship / Serotonin antagonists

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N1-(Benzenesulfonyl)tryptamines as novel 5-HT6 antagonists

Organic Chemistry / Kinetics / Serotonin / Cell line / Humans / Drug Design / Serotonin Receptors / Radioligand Assay / Transfection / Molecular Conformation / Bioorganic and medicinal Chemistry / Structure activity Relationship / Recombinant Proteins / Serotonin antagonists / Tryptamines / Drug Design / Serotonin Receptors / Radioligand Assay / Transfection / Molecular Conformation / Bioorganic and medicinal Chemistry / Structure activity Relationship / Recombinant Proteins / Serotonin antagonists / Tryptamines

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Longterm oral cisapride improves interdigestive antroduodenal motility in dyspeptic patients

Humans / Female / Digestion / Male / Dyspepsia / Clinical Sciences / Middle Aged / Adult / Time Factors / Gut / Gastrointestinal Tract / Gastrointestinal motility / Indexation / Serotonin antagonists / Piperidines / Duodenum / Motor activity / Clinical Sciences / Middle Aged / Adult / Time Factors / Gut / Gastrointestinal Tract / Gastrointestinal motility / Indexation / Serotonin antagonists / Piperidines / Duodenum / Motor activity

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Physicochemical and biopharmaceutical characterization ofendo-2-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-2,3-dihydro-1H-benz[e]isoindol-1-one (CR3124) a novel potent 5-HT3 receptor antagonist

Water / NMR Spectroscopy / Crystallization / Macromolecular X-Ray Crystallography / Molecular Dynamics / Crystal structure / Humans / Differential scanning calorimetry / Permeability / Pharmaceutical Sciences / Solubility / Intestinal absorption / Caco-2 cells / Molecular Conformation / Crystalline Structure / Serotonin antagonists / Crystal structure / Humans / Differential scanning calorimetry / Permeability / Pharmaceutical Sciences / Solubility / Intestinal absorption / Caco-2 cells / Molecular Conformation / Crystalline Structure / Serotonin antagonists

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Inactivation of 5-HT2C Receptors Potentiates Consequences of Serotonin Reuptake Blockade

Neuropsychopharmacology / Serotonin / Animals / Male / Synaptic Transmission / Microdialysis / Rats / Rat / Receptor / Wistar Rats / Brain Chemistry / Serotonin antagonists / Serotonin Uptake Inhibitors / Selective serotonin reuptake inhibitor / Microdialysis / Rats / Rat / Receptor / Wistar Rats / Brain Chemistry / Serotonin antagonists / Serotonin Uptake Inhibitors / Selective serotonin reuptake inhibitor

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Inactivation of 5-HT2C Receptors Potentiates Consequences of Serotonin Reuptake Blockade

Neuropsychopharmacology / Serotonin / Animals / Male / Synaptic Transmission / Microdialysis / Rats / Rat / Receptor / Wistar Rats / Brain Chemistry / Serotonin antagonists / Serotonin Uptake Inhibitors / Selective serotonin reuptake inhibitor / Microdialysis / Rats / Rat / Receptor / Wistar Rats / Brain Chemistry / Serotonin antagonists / Serotonin Uptake Inhibitors / Selective serotonin reuptake inhibitor

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CCKA and 5-HT3 Receptors Interact in Anorectic Responses to Amino Acid Deficiency

Diet / Animals / Male / Eating / Amino Acids / Serotonin Receptors / Rats / Rat / Deficiency / Anorexia / Deficit / Serotonin antagonists / Serotonin Receptors / Rats / Rat / Deficiency / Anorexia / Deficit / Serotonin antagonists

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